Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 4/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449100 | 1.00 | ALDH1A1 (0.35) | ALDH1A1MAPTGAANR1D1HPGD | |
| SCHEMBL8449288 | 0.91 | CCR5 (0.35) | ALDH1A1MAPTGAANR1D1HPGD | |
| SCHEMBL8448979 | 0.89 | CCR5 (0.37) | ALDH1A1MAPTNR1D1HPGDCCR5 | |
| SCHEMBL8447364 | 0.89 | CCR5 (0.37) | ALDH1A1MAPTNR1D1HPGDCCR5 | |
| SCHEMBL8447158 | 0.86 | TPSAB1 (0.39) | ALDH1A1MAPTGAADPP8DPP9 | |
| SCHEMBL8440242 | 0.84 | ALDH1A1 (0.37) | ALDH1A1MAPTGAAHPGDDPP8 | |
| SCHEMBL8439764 | 0.83 | EPHX2 (0.39) | ALDH1A1MAPTGAADPP8DPP9 | |
| SCHEMBL8447418 | 0.83 | DPP8 (0.34) | ALDH1A1MAPTNR1D1HPGDCCR5 | |
| SCHEMBL8447416 | 0.83 | DPP8 (0.34) | ALDH1A1MAPTNR1D1HPGDCCR5 | |
| SCHEMBL8447417 | 0.82 | TPSAB1 (0.39) | ALDH1A1MAPTGAADPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |