Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.43 |
| ▸ | ACE | P12821 | 5/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450247 | 0.93 | MME (0.47) | MMEACEMMP3MMP1CTSB | |
| SCHEMBL8449153 | 0.91 | ACE (0.47) | MMEACEMMP3PTGES | |
| SCHEMBL8450057 | 0.89 | MME (0.40) | MMEACEMMP3MMP1CTSB | |
| SCHEMBL8451246 | 0.88 | MME (0.47) | MMEACEMMP3CTSBPTGES | |
| SCHEMBL8450113 | 0.87 | MME (0.43) | MMEACEMMP3CTSBPTGES | |
| SCHEMBL8453092 | 0.86 | MME (0.43) | MMEACEMMP3MMP1CTSB | |
| SCHEMBL8452112 | 0.84 | MME (0.40) | MMEACEMMP3MMP1CTSB | |
| SCHEMBL8451272 | 0.84 | PTGES (0.39) | MMEACEMMP3CTSBPTGES | |
| SCHEMBL8449905 | 0.84 | MME (0.52) | MMEACEMMP3PTGES | |
| SCHEMBL8453054 | 0.83 | MME (0.42) | MMEACEMMP3CTSBECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |