SCHEMBL8449506

SCHEMBL8449506

CCNC(=O)C(N)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.51
MTNR1B P49286 1/20 0.51
PKM P14618 1/20 0.45
GAA P10253 1/20 0.43
POLB P06746 2/20 0.43
TSHR P16473 2/20 0.43
ALDH1A1 P00352 2/20 0.43
LTB4R Q15722 1/20 0.42
LTB4R2 Q9NPC1 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
METAP2 P50579 2/20 0.42
METAP1 P53582 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ADORA3 P0DMS8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10693263 0.79 PKM (0.51) MTNR1AMTNR1BPKMGAAPOLB
SCHEMBL15333659 0.79 MTNR1A (0.50) MTNR1AMTNR1BPKMGAAPOLB
SCHEMBL3746577 0.77 PKM (0.57) MTNR1AMTNR1BPKMPOLBMEN1
SCHEMBL4838617 0.77 PKM (0.57) MTNR1AMTNR1BPKMPOLBMEN1
Hydrochloric Acid SCHEMBL4196019 0.76 PKM (0.55) MTNR1AMTNR1BPKMPOLBMEN1
Hydrochloric Acid SCHEMBL28750033 0.76 PKM (0.55) MTNR1AMTNR1BPKMPOLBMEN1
SCHEMBL27480198 0.75 KMT2A (0.50) MTNR1AMTNR1BGAAPOLBTSHR
SCHEMBL4212653 0.74 PKM (0.46) MTNR1AMTNR1BPKMGAA
Hydrochloric Acid SCHEMBL27441067 0.74 KMT2A (0.48) MTNR1AMTNR1BGAAPOLBTSHR
SCHEMBL5214433 0.72 PARP10 (0.44) MTNR1AMTNR1BPKMGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0804239-B1 ANTI-STRESS, ANTI-IMPAIRMENT AND ANTI-AGING DRUG AND PROCESS FOR MANUFACTURING THEREOF RIGA DAN (RO) 1999-09-15 EP claimed