Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4212653 | 0.84 | PKM (0.46) | PARP10MTNR1AMTNR1BCYP2C19GAA | |
| SCHEMBL10969599 | 0.81 | PPARG (0.42) | PARP10MTNR1AMTNR1BCYP2C19GAA | |
| SCHEMBL11884465 | 0.80 | PARP10 (0.45) | PARP10POLBCTNNB1MTNR1AMTNR1B | |
| SCHEMBL216782 | 0.78 | PARP10 (0.44) | PARP10POLBCTNNB1MTNR1AMTNR1B | |
| SCHEMBL27480198 | 0.78 | KMT2A (0.50) | POLBMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL2007632 | 0.77 | PARP10 (0.42) | PARP10POLBCTNNB1MTNR1AMTNR1B | |
| SCHEMBL995776 | 0.77 | LDHA (0.52) | PARP10POLBCTNNB1MTNR1AMTNR1B | |
| SCHEMBL4580738 | 0.77 | PARP10 (0.42) | PARP10POLBCTNNB1MTNR1AMTNR1B | |
| SCHEMBL7408531 | 0.77 | PARP10 (0.42) | PARP10POLBCTNNB1MTNR1AMTNR1B | |
| SCHEMBL28319983 | 0.77 | PARP10 (0.42) | PARP10POLBCTNNB1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228367-B1 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | ASUBIO PHARMA CO LTD (JP) | 2007-09-26 | — | — | EP | claimed |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. | 2006-08-10 | — | — | US | claimed |
| US-7067533-B2 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. (JP) | 2006-06-27 | — | — | US | claimed |
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2003-07-24 | — | — | US | claimed |
| EP-1228367-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2002-08-07 | — | — | EP | claimed |
| WO-2001079170-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2001-10-25 | — | — | WO | claimed |
| EP-1228367-B1 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | ASUBIO PHARMA CO LTD (JP) | 2007-09-26 | — | — | EP | disclosed |
| EP-1228367-B1 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | ASUBIO PHARMA CO LTD (JP) | 2007-09-26 | — | — | EP | disclosed |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. | 2006-08-10 | — | — | US | disclosed |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. | 2006-08-10 | — | — | US | disclosed |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | DAIICHI ASUBIO PHARMA CO., LTD. | 2006-08-10 | — | — | US | disclosed |
| CN-1264821-C | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SUNTORY LTD (JP) | 2006-07-19 | — | — | CN | disclosed |
| CN-1264821-C | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SUNTORY LTD (JP) | 2006-07-19 | — | — | CN | disclosed |
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | ASUBIO PHARMA CO., LTD. (JP) | 2003-07-24 | — | — | US | disclosed |
| EP-1228367-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2002-08-07 | — | — | EP | disclosed |
| EP-1228367-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001079170-A3 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LTD (JP) | 2002-06-13 | — | — | WO | disclosed |
| WO-2001079170-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2001-10-25 | — | — | WO | disclosed |
| WO-2001079170-A2 | AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF | SUNTORY LIMITED (JP) | 2001-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139447-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | SCN10A, CAMK2A, CAMK2B | PARP10 2613/4885POLB 4526/4885CTNNB1 2439/4885 |
| US-20060178401-A1 | Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof | NR0B1, NR0B2, NR4A1 | PARP10 1202/4885POLB 3328/4885CTNNB1 3627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.