Sugi Predict

Sugi Predict / Compounds / Benzylamine

Benzylamine

Benzylamine

SCHEMBL8449809

NCc1ccccc1.O=C1CCCc2ccccc21

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 11/20 0.70
▸ MAOB P27338 11/20 0.70
▸ CYP2A6 P11509 1/20 0.70
▸ LOXL2 Q9Y4K0 1/20 0.47
▸ GRM5 P41594 1/20 0.45
▸ G6PC1 P35575 1/20 0.44
▸ MAPT P10636 1/20 0.43
▸ MIF P14174 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ CES1 P23141 1/20 0.41
▸ PRKCI P41743 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351871 0.84 MAOA (1.00) MAOAMAOBCYP2A6GRM5MAPT
SCHEMBL44545 0.84 MAOA (1.00) MAOAMAOBCYP2A6GRM5MAPT
SCHEMBL31385562 0.82 MAOA (0.95) MAOAMAOBCYP2A6GRM5MAPT
Methane SCHEMBL28944934 0.82 MAOA (0.95) MAOAMAOBCYP2A6GRM5MAPT
Benzylamine SCHEMBL7398997 0.82 LOXL2 (0.64) MAOBCYP2A6LOXL2G6PC1KMT2A
SCHEMBL5050048 0.80 MAOA (0.91) MAOAMAOBCYP2A6GRM5MAPT
SCHEMBL10456794 0.80 MAOA (0.91) MAOAMAOBCYP2A6GRM5MAPT
SCHEMBL18607288 0.80 MAOA (0.91) MAOAMAOBCYP2A6GRM5MAPT
SCHEMBL18716863 0.80 MAOA (0.91) MAOAMAOBCYP2A6GRM5MAPT
SCHEMBL29766301 0.80 MAOA (0.91) MAOAMAOBCYP2A6GRM5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901996-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES Mitsui Chemicals, Inc. (JP) 1999-03-17 — — EP disclosed