Benzylamine

Benzylamine

SCHEMBL7398997

NCc1ccccc1.c1ccc2c(c1)CCC2

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.64
TSHR P16473 2/20 0.52
TAAR1 Q96RJ0 2/20 0.48
GRIN2B Q13224 3/20 0.43
MAOB P27338 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
G6PC1 P35575 1/20 0.42
PRMT6 Q96LA8 1/20 0.41
RAD52 P43351 1/20 0.41
KMT2A Q03164 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
HTR6 P50406 1/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PNMT P11086 1/20 0.40
ENPP2 Q13822 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzylamine SCHEMBL893344 0.91 LOXL2 (0.70) LOXL2TSHRTAAR1GRIN2BMAOB
Benzylamine SCHEMBL8449809 0.82 MAOA (0.70) LOXL2MAOBG6PC1KMT2ACYP2A6
SCHEMBL24465564 0.80 LOXL2 (0.54) LOXL2TSHRTAAR1GRIN2BPRMT6
Benzylamine SCHEMBL10707644 0.80 LOXL2 (1.00) LOXL2TSHRTAAR1MAOBCYP1A2
Benzylamine SCHEMBL1331207 0.80
Benzylamine SCHEMBL373 0.80
Benzylamine SCHEMBL5481672 0.80 LOXL2 (1.00) LOXL2TSHRTAAR1MAOBCYP1A2
SCHEMBL19242392 0.80 LOXL2 (1.00) LOXL2TSHRTAAR1MAOBCYP1A2
Benzylamine SCHEMBL15270988 0.79 LOXL2 (0.48) LOXL2TSHRTAAR1MAOBCYP1A2
Hydrazine SCHEMBL2172540 0.77 TSHR (0.75) TSHRMAOBCYP2A6PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100566712-C Polyamine compounds for the treatment of chemokine receptor mediated diseases TAIGEN BIOTECHNOLOGY CO LTD (CN) 2009-12-09 CN disclosed
CN-1798551-A Polyamine compounds for the treatment of chemokine receptor mediated diseases TAIGEN BIOTECHNOLOGY CO LTD (CN) 2006-07-05 CN disclosed
EP-0738149-A4 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF TEVA PHARMA (IL) 1999-10-27 EP disclosed
US-5880159-A TREATING ACUTE NEUROLOGICAL TRAUMATIC DISORDER OR NEUROTRAUMA TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 1999-03-09 US disclosed
EP-0738149-A1 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 1996-10-23 EP disclosed
WO-1995018617-A1 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 1995-07-13 WO disclosed