Sugi Predict

Sugi Predict / Compounds / SCHEMBL844986

SCHEMBL844986

SCHEMBL844986

Nc1ccc(Br)c2c1CCCC2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IL1RN P18510 1/20 0.37
▸ ERAP2 Q6P179 1/20 0.37
▸ ERAP1 Q9NZ08 1/20 0.37
▸ HTR2C P28335 1/20 0.34
▸ NOS3 P29474 1/20 0.33
▸ NOS1 P29475 1/20 0.33
▸ NOS2 P35228 1/20 0.33
▸ ACHE P22303 7/20 0.33
▸ BCHE P06276 5/20 0.33
▸ GRIN1 Q05586 5/20 0.33
▸ GRIN2A Q12879 5/20 0.33
▸ AXL P30530 1/20 0.32
▸ ALDH1A1 P00352 3/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ MAPT P10636 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ POLB P06746 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21451647 0.98 IL1RN (0.36) IL1RNERAP2ERAP1HTR2CNOS3
SCHEMBL14711738 0.95 IL1RN (0.37) IL1RNERAP2ERAP1HTR2CACHE
SCHEMBL4823261 0.84 NOS3 (0.41) NOS3NOS1NOS2ACHEBCHE
SCHEMBL10463782 0.84 HTR2C (0.40) IL1RNERAP2ERAP1HTR2CNOS3
Hydrochloric Acid SCHEMBL4817979 0.82 NOS3 (0.39) NOS3NOS1NOS2ACHEBCHE
SCHEMBL21451652 0.82 NOS3 (0.39) NOS3NOS1NOS2ACHEBCHE
SCHEMBL30509287 0.79 HTR2C (0.40) IL1RNERAP2ERAP1HTR2CACHE
SCHEMBL13249026 0.79 HTR2C (0.40) IL1RNERAP2ERAP1HTR2CACHE
SCHEMBL4822580 0.79 ACHE (0.36) NOS3NOS1NOS2ACHEBCHE
Hydrochloric Acid SCHEMBL4821905 0.76 ACHE (0.35) NOS3NOS1NOS2ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435066-B2 Substituted tricyclic compounds LUPIN LIMITED (IN) 2025-10-07 — — US disclosed
CN-114746411-B Substituted tricyclic compounds 印度鲁宾有限公司 2024-06-25 — — CN disclosed
US-11891369-B2 Compounds for binding proprotein convertase subtilisin/kexin type 9 SRX CARDIO, LLC (US) 2024-02-06 — — US disclosed
EP-4065575-B1 SUBSTITUTED TRICYCLIC COMPOUNDS LUPIN LTD (IN) 2024-01-31 — — EP disclosed
US-20230013778-A1 SUBSTITUTED TRICYCLIC COMPOUNDS LUPIN LIMITED (IN) 2023-01-19 — — US disclosed
EP-4065575-A1 SUBSTITUTED TRICYCLIC COMPOUNDS Lupin Limited (IN) 2022-10-05 — — EP disclosed
CN-114746411-A Substituted tricyclic compounds 印度鲁宾有限公司 2022-07-12 — — CN disclosed
WO-2021105960-A1 SUBSTITUTED TRICYCLIC COMPOUNDS LUPIN LIMITED (IN) 2021-06-03 — — WO disclosed
WO-2021105960-A1 SUBSTITUTED TRICYCLIC COMPOUNDS LUPIN LIMITED (IN) 2021-06-03 — — WO disclosed
US-20210032214-A1 COMPOUNDS FOR BINDING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 SRX CARDIO, LLC 2021-02-04 — — US disclosed
EP-2476715-A2 Polymer compound, luminescent material, and light emitting element Sumitomo Chemical Co., Ltd (JP) 2012-07-18 — — EP disclosed
EP-1935943-B1 POLYMER COMPOUND, LUMINESCENT MATERIAL, AND LIGHT EMITTING ELEMENT SUMITOMO CHEMICAL CO (JP) 2012-03-28 — — EP disclosed
US-20100298295-A1 2-BIPHENYLAMINO-4-AMINOPYRIMIDINE DERIVATIVES AS KINASE INHIBITORS IRM LLC (BM) 2010-11-25 — — US disclosed
EP-2190826-A2 2-BIPHENYLAMINO-4-AMINOPYRIMIDINE DERIVATIVES AS KINASE INHIBITORS IRM LLC (BM) 2010-06-02 — — EP disclosed
WO-2009032668-A2 2 -BIPHENYLAMINO-4 -AMINOPYRIMIDINE DERIVATIVES AS KINASE INHIBITORS IRM LLC (BM) 2009-03-12 — — WO disclosed
US-20080254320-A1 Mixture of polymer and phosphorescence compound ; electronics SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-16 — — US disclosed
US-20080254320-A1 Mixture of polymer and phosphorescence compound ; electronics SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-16 — — US disclosed
US-20080254320-A1 Mixture of polymer and phosphorescence compound ; electronics SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-16 — — US disclosed
EP-1935943-A1 POLYMER COMPOUND, LUMINESCENT MATERIAL, AND LIGHT EMITTING ELEMENT Sumitomo Chemical Company, Limited (JP) 2008-06-25 — — EP disclosed
EP-0638237-A1 ATTRACTANT AND FEEDING STIMULANT FOR COCKROACH TAISHO PHARMACEUTICAL CO. LTD (JP) 1995-02-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891369-B2 Compounds for binding proprotein convertase subtilisin/kexin type 9 PCSK9, PCSK6, PCSK7 IL1RN 500/4885ERAP2 1005/4885ERAP1 808/4885
US-20230013778-A1 SUBSTITUTED TRICYCLIC COMPOUNDS SOS1, RSU1, KSR1 IL1RN 1090/4885ERAP2 4716/4885ERAP1 3303/4885
US-20210032214-A1 COMPOUNDS FOR BINDING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 PCSK9, PCSK6, PCSK7 IL1RN 625/4885ERAP2 1501/4885ERAP1 1203/4885
US-20100298295-A1 2-BIPHENYLAMINO-4-AMINOPYRIMIDINE DERIVATIVES AS KINASE INHIBITORS IGF1R, IGFBP1, IRS1 IL1RN 101/4885ERAP2 2994/4885ERAP1 2605/4885
US-12435066-B2 Substituted tricyclic compounds SOS1, RSU1, KSR1 IL1RN 1090/4885ERAP2 4716/4885ERAP1 3303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.