Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.40 |
| ▸ | ACE | P12821 | 4/20 | 0.40 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450833 | 0.90 | MME (0.42) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7567819 | 0.89 | MME (0.53) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7567828 | 0.89 | MME (0.53) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8447129 | 0.88 | MME (0.41) | MMEACEMMEL1KDM4EMAPT | |
| SCHEMBL8447132 | 0.87 | MME (0.40) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8449910 | 0.87 | MME (0.46) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8450138 | 0.86 | MMEL1 (0.47) | MMEACEMMEL1KDM4EPPARG | |
| SCHEMBL8450803 | 0.85 | MME (0.48) | MMEACECTSBACACBMEN1 | |
| SCHEMBL8447086 | 0.83 | MME (0.44) | MMEACEALDH1A1PPARGCTSB | |
| SCHEMBL8449917 | 0.82 | MMEL1 (0.35) | MMEACEMMEL1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |