Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.41 |
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447132 | 0.96 | MME (0.40) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8450833 | 0.95 | MME (0.42) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8449504 | 0.88 | MME (0.40) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8449913 | 0.88 | MME (0.40) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7566387 | 0.88 | MME (0.55) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7566393 | 0.88 | MME (0.55) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8450138 | 0.87 | MMEL1 (0.47) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL8447126 | 0.85 | MME (0.46) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7574128 | 0.84 | MME (0.53) | MMEACEMMEL1PPARGPPARD | |
| SCHEMBL7570073 | 0.84 | MME (0.53) | MMEACEMMEL1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |