Acetic Acid Methyl Ester

Acetic Acid Methyl Ester

SCHEMBL28504359

COC(C)=O.c1ccc(CSOSCc2ccccc2)cc1

nearest known ligand 0.48

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
L3MBTL1 Q9Y468 3/20 0.44
PKM P14618 1/20 0.43
FFAR1 O14842 1/20 0.43
MAPK1 P28482 1/20 0.43
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
LMNA P02545 1/20 0.42
CYP2C19 P33261 1/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
CTRB1 P17538 1/20 0.41
PTGS2 P35354 1/20 0.41
ATM Q13315 1/20 0.40
CYP2C9 P11712 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28067210 0.86 LMNA (0.41) ALDH1A1L3MBTL1PKMFFAR1MAPK1
Acetic Acid SCHEMBL28536489 0.85 ALDH1A1 (0.44) ALDH1A1L3MBTL1GAALMNACYP2C19
Acetic Acid Methyl Ester SCHEMBL23070551 0.85 CYP2C19 (0.53) ALDH1A1L3MBTL1PKMFFAR1MAPK1
SCHEMBL28121204 0.84 ALDH1A1 (0.41) ALDH1A1L3MBTL1PKMGAACYP2C19
SCHEMBL8450 0.82 IDO1 (0.44) CYP2C19POLB
SCHEMBL28063243 0.82 MTNR1A (0.41) ALDH1A1L3MBTL1LMNACYP2C9
SCHEMBL10519643 0.81 ALDH1A1 (0.52) ALDH1A1L3MBTL1PKMFFAR1MAPK1
Acetic Acid SCHEMBL28365922 0.81 ALDH1A1 (0.47) ALDH1A1L3MBTL1PKMFFAR1MAPK1
Water SCHEMBL28337532 0.80 IDO1 (0.43) CYP2C19POLB
Phenylacetaldehyde SCHEMBL29232774 0.77 ALDH1A1 (0.52) ALDH1A1L3MBTL1GAALMNACTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483352-B Co-production method of thiourethane and benzyl thioether-based acetic acid and application of co-production method in flotation 中南大学 2021-03-16 CN claimed
CN-110523541-B Alkyl thioether ether ethyl hydroximic acid medicament and preparation method and application thereof 中南大学 2021-09-28 CN disclosed
CN-110563621-B Method for utilizing byproduct sodium 2-mercaptoacetate in thiourethane production process 中南大学 2021-01-22 CN disclosed