Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.47 |
| ▸ | PADI3 | Q9ULW8 | 2/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134702 | 0.91 | CA2 (0.53) | PYGLCYP2C9MMEPADI1PADI3 | |
| SCHEMBL4775100 | 0.84 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL30615313 | 0.84 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL29772335 | 0.84 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL4775097 | 0.84 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL30615312 | 0.84 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL2329886 | 0.84 | ALDH1A1 (0.56) | ALDH1A1FNTAFNTB | |
| SCHEMBL2329890 | 0.84 | ALDH1A1 (0.56) | ALDH1A1FNTAFNTB | |
| SCHEMBL2331801 | 0.84 | PADI1 (0.44) | PYGLCYP2C9PADI1PADI3PADI4 | |
| SCHEMBL10023942 | 0.83 | PADI1 (0.52) | PYGLCYP2C9PADI1PADI3PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143283-B1 | Methods for treating blood-born tumors with thalidomide | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |