Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 3/20 | 0.52 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.52 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.52 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134702 | 0.87 | CA2 (0.53) | PADI1PADI3PADI4PADI2HTT | |
| SCHEMBL4775097 | 0.83 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL29772335 | 0.83 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL30615313 | 0.83 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL30615312 | 0.83 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL845137 | 0.83 | PYGL (0.50) | PADI1PADI3PADI4HTTKMT2A | |
| SCHEMBL4775100 | 0.83 | NAALAD2 (0.56) | PADI1PADI3PADI4KDM4ENFKB1 | |
| SCHEMBL10023118 | 0.81 | KMT2A (0.57) | PADI1PADI3PADI4PADI2KMT2A | |
| SCHEMBL30056283 | 0.80 | CA1 (0.49) | PADI1PADI3PADI4KMT2AAPEX1 | |
| SCHEMBL2331801 | 0.79 | PADI1 (0.44) | PADI1PADI3PADI4PADI2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142734-A1 | METHODS FOR TREATING TUMORS WITH THALIDOMIDE | THE CHILDREN'S MEDICAL CENTER CORPORATION | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142734-A1 | METHODS FOR TREATING TUMORS WITH THALIDOMIDE | PGF, FLT4, HIF1AN | PADI1 3765/4885PADI3 3466/4885PADI4 3242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.