SCHEMBL8453044

SCHEMBL8453044

CCC(N)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
CASP3 P42574 4/20 0.53
EPHX2 P34913 1/20 0.50
MDM4 O15151 1/20 0.47
TP53 P04637 1/20 0.47
TLR2 O60603 1/20 0.45
PIN1 Q13526 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3162296 0.99 KMT2A (0.55) KMT2ACASP3EPHX2MDM4TP53
Bromide SCHEMBL15640173 0.88 KMT2A (0.53) KMT2ACASP3EPHX2TLR2
Hydrochloric Acid SCHEMBL2524994 0.88 KMT2A (0.53) KMT2ACASP3EPHX2TLR2
SCHEMBL992905 0.86 TLR2 (0.54) KMT2ACASP3EPHX2TLR2
Bromide SCHEMBL19100909 0.85 TLR2 (0.54) KMT2ACASP3EPHX2TLR2
SCHEMBL6795717 0.85 KMT2A (0.54) KMT2ACASP3EPHX2MDM4TP53
SCHEMBL608620 0.84 KMT2A (0.54) KMT2ACASP3EPHX2MDM4TP53
SCHEMBL2625076 0.83 KMT2A (0.58) KMT2ACASP3EPHX2MDM4TP53
SCHEMBL16000763 0.83 KMT2A (0.52) KMT2ACASP3EPHX2MDM4TP53
SCHEMBL178787 0.83 MDM4 (0.60) KMT2ACASP3MDM4TP53TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10501499-B2 Peptides derived from viral proteins for use as immunogens and dosage reactants BIONOR IMMUNO AS (NO) 2019-12-10 US disclosed
US-10124059-B2 Dimeric scaffold peptides comprising HIV-1 GP120 and GP41 epitopes BIONOR IMMUNO AS (NO) 2018-11-13 US disclosed
EP-3338798-A1 MULTIMERIC PEPTIDE Bionor Immuno AS (NO) 2018-06-27 EP disclosed
US-20160375129-A1 DIMERIC SCAFFOLD PEPTIDES COMPRISING HIV-1 GP120 AND GP41 EPITOPES BIONOR IMMUNO AS (NO) 2016-12-29 US disclosed
US-9493514-B2 Dimeric scaffold proteins comprising HIV-1 GP120 and GP41 epitopes BIONOR IMMUNO AS (NO) 2016-11-15 US disclosed
US-20150152140-A1 PEPTIDES DERIVED FROM VIRAL PROTEINS FOR USE AS IMMUNOGENS AND DOSAGE REACTANTS BIONOR IMMUNO AS (NO) 2015-06-04 US disclosed
EP-2859011-A1 PEPTIDES DERIVED FROM VIRAL PROTEINS FOR USE AS IMMUNOGENS AND DOSAGE REACTANTS Bionor Immuno AS (NO) 2015-04-15 EP disclosed
US-20140044746-A1 MONOMERIC AND MULTIMERIC IMMUNOGENIC PEPTIDES BIONOR IMMUNO AS (NO) 2014-02-13 US disclosed
WO-2013182661-A1 PEPTIDES DERIVED FROM VIRAL PROTEINS FOR USE AS IMMUNOGENS AND DOSAGE REACTANTS BIONOR IMMUNO AS (NO) 2013-12-12 WO disclosed
EP-2661442-A1 MONOMERIC AND MULTIMERIC IMMUNOGENIC PEPTIDES Bionor Immuno AS (NO) 2013-11-13 EP disclosed
WO-2012092934-A1 MONOMERIC AND MULTIMERIC IMMUNOGENIC PEPTIDES BIONOR IMMUNO AS (NO) 2012-07-12 WO disclosed
WO-2010023295-A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-03-04 WO disclosed
US-5919523-A Derivatization of solid supports and methods for oligomer synthesis AFFYMETRIX, INC. (US) 1999-07-06 US disclosed
US-5624711-A AFFIXING FUNCTIONAL SITES TO THE SURFACE OF A SOLID SUBSTRATE AFFYMAX TECHNOLOGIES, N.V. (NL) 1997-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160375129-A1 DIMERIC SCAFFOLD PEPTIDES COMPRISING HIV-1 GP120 AND GP41 EPITOPES CD4, HAVCR2, MAVS KMT2A 4328/4885CASP3 2057/4885EPHX2 4456/4885
US-10124059-B2 Dimeric scaffold peptides comprising HIV-1 GP120 and GP41 epitopes CD4, HAVCR2, MAVS KMT2A 4328/4885CASP3 2057/4885EPHX2 4456/4885
US-20140044746-A1 MONOMERIC AND MULTIMERIC IMMUNOGENIC PEPTIDES HLA-DRB1, CXCL10, CXCR3 KMT2A 4712/4885CASP3 1217/4885EPHX2 4525/4885
US-10501499-B2 Peptides derived from viral proteins for use as immunogens and dosage reactants HAVCR2, CXCL10, CCL5 KMT2A 4395/4885CASP3 4245/4885EPHX2 4253/4885
US-20150152140-A1 PEPTIDES DERIVED FROM VIRAL PROTEINS FOR USE AS IMMUNOGENS AND DOSAGE REACTANTS HAVCR2, CXCL10, CCL5 KMT2A 4395/4885CASP3 4245/4885EPHX2 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.