Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28086039 | 0.96 | ALDH1A1 (0.48) | ALDH1A1TSHRCA2CA1CA9 | |
| Bicarbonate SCHEMBL9083427 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TSHRCA2HSD17B10 | |
| Bicarbonate SCHEMBL27364872 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TSHRCA2HSD17B10 | |
| Acetic Acid SCHEMBL774951 | 0.89 | FFAR3 (0.50) | ALDH1A1TSHRCA2FFAR3HSD17B10 | |
| Acetic Acid SCHEMBL7261899 | 0.89 | FFAR3 (0.50) | ALDH1A1TSHRCA2FFAR3HSD17B10 | |
| Hydrogen Peroxide SCHEMBL6441406 | 0.88 | — | — | |
| Bicarbonate SCHEMBL2399348 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TSHRCA2HPGDHCAR2 | |
| Bicarbonate SCHEMBL10449780 | 0.85 | ALDH1A1 (0.41) | ALDH1A1TSHRCA2HPGDHSD17B10 | |
| Bicarbonate SCHEMBL10845069 | 0.85 | TDP1 (0.56) | ALDH1A1TSHRCA2FFAR3 | |
| Acetone SCHEMBL8319174 | 0.85 | LMNA (0.46) | ALDH1A1TSHRHSD17B10MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113994517-B | Electrolyte for high voltage cathode materials and other uses | 飞翼新能源公司 | 2025-01-28 | — | — | CN | claimed |
| CN-113994517-B | Electrolyte for high voltage cathode materials and other uses | 飞翼新能源公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-113924676-B | Electrodes for lithium ion batteries and other uses | 飞翼新能源公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-118281344-A | Nonaqueous electrolyte composition | 法拉典有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-112072072-A | Pre-cycled silicon electrode | 通用汽车环球科技运作有限责任公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-111433960-A | Nonaqueous electrolyte composition | 法拉典有限公司 | 2020-07-17 | — | — | CN | disclosed |
| CN-106165150-B | The manufacturing method of diaphragm | 住友化学株式会社 | 2019-06-18 | — | — | CN | disclosed |
| CN-109378428-A | Laminated porous film and manufacturing method, nonaqueous electrolytic solution secondary battery diaphragm, multilayer electrode piece and nonaqueous electrolytic solution secondary battery | 住友化学株式会社 | 2019-02-22 | — | — | CN | disclosed |
| CN-106163791-B | Laminated porous film and nonaqueous electrolyte secondary battery | 住友化学株式会社 | 2018-05-25 | — | — | CN | disclosed |
| CN-107922379-A | Substituted guanidine derivatives | 宇部兴产株式会社 | 2018-04-17 | — | — | CN | disclosed |
| EP-3158604-A1 | SEMI-SOLID ELECTROLYTES FOR BATTERIES | Medtronic, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |
| CN-106163791-A | Laminated porous film and nonaqueous electrolyte secondary battery | 住友化学株式会社 | 2016-11-23 | — | — | CN | disclosed |
| CN-106165150-A | The manufacture method of barrier film | 住友化学株式会社 | 2016-11-23 | — | — | CN | disclosed |
| WO-2015195595-A1 | SEMI-SOLID ELECTROLYTES FOR BATTERIES | MEDTRONIC, INC. (US) | 2015-12-23 | — | — | WO | disclosed |
| WO-1999049527-A1 | LOW TEMPERATURE SYNTHESIS OF Li4Mn5O12 CATHODES FOR LITHIUM BATTERIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-09-30 | — | — | WO | disclosed |
| WO-1996032752-A1 | CURABLE ALKANE MULTIFUNCTIONAL ACRYLATES BASED SOLID ELECTROLYTES AND ELECTROLYTIC CELLS PRODUCED THEREFROM | VALENCE TECHNOLOGY, INC. (US) | 1996-10-17 | — | — | WO | disclosed |
| WO-1996032754-A1 | PROCESS FOR PRELITHIATION OF CARBON BASED ANODES FOR LITHIUM BATTERIES | VALENCE TECHNOLOGY, INC. (US) | 1996-10-17 | — | — | WO | disclosed |