Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP3 | Q9NSD7 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844852 | 0.90 | L3MBTL1 (0.63) | RXFP3L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL844889 | 0.81 | RXFP3 (0.51) | RXFP3L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL845527 | 0.77 | L3MBTL1 (0.51) | RXFP3L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL13485761 | 0.76 | L3MBTL1 (0.74) | RXFP3L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL845806 | 0.75 | L3MBTL1 (0.46) | RXFP3L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL844886 | 0.71 | ALDH1A1 (0.62) | RXFP3L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL13272274 | 0.70 | L3MBTL1 (0.43) | RXFP3L3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL2449353 | 0.70 | L3MBTL1 (1.00) | RXFP3L3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27001821 | 0.69 | RXFP3 (1.00) | RXFP3MAPT | |
| SCHEMBL18887500 | 0.69 | RXFP3 (0.51) | RXFP3L3MBTL1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |