Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844988 | 0.96 | HPGD (0.43) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL2197678 | 0.80 | HPGD (0.43) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL845344 | 0.79 | MEN1 (0.44) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL844993 | 0.76 | MMP2 (0.40) | KMT2AMEN1NPC1RAB9ACYP2C9 | |
| SCHEMBL845500 | 0.75 | HPGD (0.51) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL845495 | 0.75 | HPGD (0.51) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL872291 | 0.75 | F2 (0.41) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL845457 | 0.74 | HPGD (0.55) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL845778 | 0.73 | CTSS (0.43) | KMT2AMEN1ALDH1A1POLBCYP2C9 | |
| SCHEMBL872441 | 0.73 | HPGD (0.38) | KMT2AMEN1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |