Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 1/20 | 0.48 |
| ▸ | RHOA | P61586 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 6/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119346 | 0.96 | RHOC (0.45) | RHOCRHOADGAT1F10EP300 | |
| SCHEMBL845841 | 0.92 | TRPV1 (0.45) | DGAT1HCRTR1HTT | |
| SCHEMBL13272509 | 0.92 | TRPV1 (0.45) | DGAT1HCRTR1HTT | |
| SCHEMBL845114 | 0.90 | EP300 (0.46) | RHOCRHOADGAT1F10EP300 | |
| SCHEMBL845704 | 0.88 | TRPV1 (0.48) | DGAT1HCRTR1HTT | |
| SCHEMBL10119343 | 0.87 | ALDH1A1 (0.44) | DGAT1F2L3MBTL1 | |
| SCHEMBL10119342 | 0.86 | ALDH1A1 (0.45) | RHOCRHOADGAT1EP300CREBBP | |
| SCHEMBL845640 | 0.85 | ALDH1A1 (0.49) | HCRTR1 | |
| SCHEMBL845442 | 0.84 | CYP2C9 (0.43) | RHOCRHOAHTT | |
| SCHEMBL10119326 | 0.83 | EP300 (0.41) | RHOCRHOADGAT1EP300CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| EP-1893573-B1 | INHIBITORS OF HCV REPLICATION | BRISTOL MYERS SQUIBB CO (US) | 2010-07-21 | — | — | EP | disclosed |