Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.65 |
| ▸ | RARG | P13631 | 12/20 | 0.65 |
| ▸ | RARA | P10276 | 11/20 | 0.65 |
| ▸ | RXRA | P19793 | 3/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 7/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461689 | 0.83 | RARA (0.55) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9746853 | 0.79 | RARB (0.65) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL6372648 | 0.79 | RARB (1.00) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL10544159 | 0.78 | RARB (0.79) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL3838094 | 0.78 | RARB (0.57) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9746456 | 0.77 | RARA (0.63) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9822510 | 0.76 | RARB (0.61) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9747949 | 0.73 | RARB (0.71) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL8458824 | 0.72 | RXRA (1.00) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9822546 | 0.71 | RXRA (0.64) | RARBRARGRARARXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048529-A1 | RETINOID-GLITAZONE COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-30 | — | — | WO | disclosed |