Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.63 |
| ▸ | RARB | P10826 | 9/20 | 0.63 |
| ▸ | RARG | P13631 | 9/20 | 0.63 |
| ▸ | RXRA | P19793 | 3/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746771 | 0.81 | RARA (0.51) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL10834477 | 0.80 | RARB (0.59) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL2095481 | 0.79 | RXRA (0.57) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9747144 | 0.78 | RARA (0.40) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL6372648 | 0.77 | RARB (1.00) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL8457553 | 0.77 | RARB (0.65) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9746853 | 0.77 | RARB (0.65) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9822510 | 0.77 | RARB (0.61) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL10544159 | 0.76 | RARB (0.79) | RARARARBRARGRXRACYP26A1 | |
| SCHEMBL9746493 | 0.76 | RARB (0.71) | RARARARBRARGRXRACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220118-B1 | BICYCLIC NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-01-02 | — | — | EP | claimed |
| US-4177185-A | PHENOL-ALDEHYDE RESIN AND POLYMERIC PHOSPHORYL NITRIDE OXIDE OR PRECURSOR THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | claimed |
| US-4845162-A | CLEAR, WINDOWS, WINDSHIELDS, MOLDING MATERIALS | ALLIED-SIGNAL INC. (US) | 1989-07-04 | — | — | US | disclosed |
| US-4826969-A | SKIN AND EYE DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-05-02 | — | — | US | disclosed |
| US-4177185-A | PHENOL-ALDEHYDE RESIN AND POLYMERIC PHOSPHORYL NITRIDE OXIDE OR PRECURSOR THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |
| US-4177185-A | PHENOL-ALDEHYDE RESIN AND POLYMERIC PHOSPHORYL NITRIDE OXIDE OR PRECURSOR THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |