Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8459531 | 0.88 | EDNRB (0.34) | — | |
| Hydrochloric Acid SCHEMBL8460988 | 0.87 | HTR1A (0.35) | — | |
| Hydrochloric Acid SCHEMBL8462569 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL8459119 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL8461183 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL8461390 | 0.84 | DRD2 (0.34) | — | |
| SCHEMBL8458423 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL8459045 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL138389 | 0.76 | CHRNB2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL30203878 | 0.76 | CHRNB2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653433-B1 | Novel transition metal compound, olefin polymerization catalyst component comprising the transition metal compound, olefin polymerization catalyst comprising the olefin polymerization catalyst component, and process for olefin polymerization | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0653433-A1 | Novel transition metal compound, olefin polymerization catalyst component comprising the transition metal compound, olefin polymerization catalyst comprising the olefin polymerization catalyst component, and process for olefin polymerization | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |