Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.68 |
| ▸ | RARB | P10826 | 13/20 | 0.61 |
| ▸ | RARG | P13631 | 13/20 | 0.61 |
| ▸ | RARA | P10276 | 12/20 | 0.61 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.47 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565654 | 0.87 | RXRA (0.51) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL8101908 | 0.84 | RARB (0.72) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7709227 | 0.83 | CYP3A4 (0.59) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL10565430 | 0.82 | RARB (0.70) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL27324962 | 0.82 | RARB (0.66) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL8776323 | 0.82 | RARA (0.57) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL7713109 | 0.82 | CYP3A4 (0.66) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL8776329 | 0.82 | RARA (0.57) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL8458824 | 0.81 | RXRA (1.00) | RXRARARBRARGRARACYP26A1 | |
| SCHEMBL10565189 | 0.79 | RARA (0.49) | RXRARARBRARGRARACYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048529-A1 | RETINOID-GLITAZONE COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-30 | — | — | WO | disclosed |
| EP-0808159-A1 | USE OR RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024344-A1 | USE OF RETINOIDS TO LOWER PLASMA LEVELS OF LIPOPROTEIN (a) | WARNER-LAMBERT COMPANY (US) | 1996-08-15 | — | — | WO | disclosed |
| US-5489611-A | ADMINISTERING A RETINOID COMPOUND | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |
| US-4829080-A | SKIN DISORDERS, PSORIASIS, ACNE | L'OREAL (FR) | 1989-05-09 | — | — | US | disclosed |