SCHEMBL8459234

SCHEMBL8459234

O=C(O)c1ccc(C=Cc2ccc(C(=O)O)cc2)cc1.O=C(O)c1cccc(C(=O)O)c1S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.46
TTR P02766 2/20 0.44
ALOX15 P16050 1/20 0.44
KMT2A Q03164 3/20 0.43
ALDH1A1 P00352 1/20 0.43
PIM1 P11309 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PARP1 P09874 1/20 0.42
PTPN1 P18031 4/20 0.41
HNF4A P41235 1/20 0.41
PTPN2 P17706 2/20 0.41
PTPN6 P29350 2/20 0.41
HDAC1 Q13547 1/20 0.41
ABL1 P00519 1/20 0.41
EGFR P00533 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8459232 1.00 FBP1 (0.46) FBP1TTRALOX15KMT2AALDH1A1
Terephthalic Acid SCHEMBL17685563 0.90 ALOX15 (0.52) ALOX15ALDH1A1KDM4EPOLBPTPN1
Terephthalic Acid SCHEMBL20545564 0.88 ALOX15 (0.50) ALOX15ALDH1A1KDM4EPOLBPTPN1
Terephthalic Acid SCHEMBL7867064 0.88 ALOX15 (0.50) ALOX15ALDH1A1KDM4EPOLBPTPN1
Terephthalic Acid SCHEMBL8092861 0.83 ALOX15 (0.46) ALOX15KMT2AALDH1A1KDM4EMEN1
Terephthalic Acid SCHEMBL17457900 0.83 PTPN1 (0.49) ALOX15KMT2AKDM4EMEN1PTPN1
SCHEMBL65889 0.82 ALOX15 (0.59) ALOX15ALDH1A1KDM4ESMN1; SMN2CYP2D6
Benzene SCHEMBL10638262 0.82 ALOX15 (0.59) ALOX15ALDH1A1KDM4ESMN1; SMN2CYP2D6
Terephthalic Acid SCHEMBL7867067 0.81 ALOX15 (0.44) ALOX15KMT2AALDH1A1KDM4EPOLB
Phosphine SCHEMBL3135561 0.80 ALOX15 (0.57) ALOX15ALDH1A1KDM4ESMN1; SMN2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5910363-A PAPER OF MONOFILAMENT POYESTER YARNS WITH POLYCARBODIIMIDES TO STABILIZE EASTMAN CHEMICAL COMPANY (US) 1999-06-08 US disclosed
EP-0828793-B1 POLYESTERS OF 2,6-NAPHTHALENEDICARBOXYLIC ACID HAVING IMPROVED HYDROLYTIC STABILITY EASTMAN CHEM CO (US) 1999-04-28 EP disclosed
US-5804626-A INCLUDES POLYMERIC CARBODIIMIDES ROGERS MARTIN EMERSON (US) 1998-09-08 US disclosed
EP-0828793-A1 POLYESTERS OF 2,6-NAPHTHALENEDICARBOXYLIC ACID HAVING IMPROVED HYDROLYTIC STABILITY EASTMAN CHEMICAL COMPANY (US) 1998-03-18 EP disclosed
US-5607757-A Paper machine fabric EASTMAN CHEMICAL COMPANY (US) 1997-03-04 US disclosed
WO-1996038504-A1 POLYESTERS OF 2,6-NAPHTHALENEDICARBOXYLIC ACID HAVING IMPROVED HYDROLYTIC STABILITY EASTMAN CHEMICAL COMPANY (US) 1996-12-05 WO disclosed