Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196233 | 0.98 | LMNA (0.50) | LMNAGPR84FFAR1MAPTFDPS | |
| SCHEMBL27538738 | 0.98 | LMNA (0.50) | LMNAGPR84FFAR1MAPTFDPS | |
| SCHEMBL5274110 | 0.95 | LMNA (0.43) | LMNAGPR84FFAR1MAPTOPRM1 | |
| SCHEMBL9263682 | 0.93 | LMNA (0.46) | LMNAGPR84FFAR1MAPTFDPS | |
| SCHEMBL8705110 | 0.93 | LMNA (0.46) | LMNAGPR84FFAR1MAPTFDPS | |
| SCHEMBL444298 | 0.91 | ALDH1A1 (0.43) | LMNAGPR84FFAR1MAPTOPRM1 | |
| SCHEMBL9262114 | 0.89 | LMNA (0.46) | LMNAGPR84FFAR1MAPTFDPS | |
| SCHEMBL8459302 | 0.89 | LMNA (0.46) | LMNAGPR84FFAR1MAPTFDPS | |
| SCHEMBL6464272 | 0.86 | FAAH (0.48) | LMNAFFAR1MAPTFFAR4 | |
| SCHEMBL10580211 | 0.85 | ALDH1A1 (0.43) | LMNAGPR84FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | claimed |
| US-5352689-A | Rhizoxin derivatives and their use as anti-tumor agents | SANKYO COMPANY, LIMITED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0350315-B1 | RHIZOXIN DERIVATES AND THEIR USE AS ANTI-TUMOR AGENTS | SANKYO COMPANY LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |