Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461622 | 0.80 | CES2 (0.42) | NPC1RAB9AALDH1A1HPGDMAPT | |
| SCHEMBL8458233 | 0.78 | MAPT (0.46) | RAB9AATMGAAL3MBTL1MAPT | |
| SCHEMBL21359198 | 0.76 | CXCL8 (0.54) | ALDH1A1GAAL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL8459795 | 0.76 | CXCL8 (0.59) | TTRS100A4PTPRCNPC1RAB9A | |
| SCHEMBL27370571 | 0.74 | CXCL8 (0.52) | ALDH1A1GAAL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL8014885 | 0.70 | S100A4 (0.86) | TTRS100A4PTPRCNPC1RAB9A | |
| SCHEMBL31268599 | 0.70 | S100A4 (0.86) | TTRS100A4PTPRCNPC1RAB9A | |
| SCHEMBL27560697 | 0.70 | TTR (0.72) | TTRS100A4PTPRCNPC1RAB9A | |
| SCHEMBL4642778 | 0.70 | MAPT (0.61) | TTRS100A4PTPRCNPC1RAB9A | |
| SCHEMBL13849150 | 0.69 | TTR (0.63) | TTRS100A4PTPRCNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859042-A | ALOPECIA, ACNE, DISEASES OF THE PROSTATE GLANDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | claimed |