Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.33 |
| ▸ | GLRB | P48167 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461190 | 0.74 | ASPH (0.38) | ASPHGRIK1AKR1C3AKR1C2NOTUM | |
| SCHEMBL8461706 | 0.73 | CES2 (0.43) | ASPHAKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL8464783 | 0.73 | ASPH (0.40) | ASPHGRIK1AKR1C3AKR1C2NOTUM | |
| SCHEMBL1635186 | 0.73 | ASPH (0.46) | ASPHGRIK1AKR1C3AKR1C2NOTUM | |
| SCHEMBL1100670 | 0.73 | ASPH (0.42) | ASPHGRIK1AKR1C3AKR1C2NOTUM | |
| SCHEMBL9185655 | 0.73 | ASPH (0.39) | ASPHNOTUMKDM4EALDH1A1HPGD | |
| SCHEMBL1098875 | 0.72 | ASPH (0.44) | ASPHAKR1C2NOTUMKDM4EALDH1A1 | |
| SCHEMBL29404413 | 0.72 | ASPH (0.44) | ASPHAKR1C2NOTUMKDM4EALDH1A1 | |
| SCHEMBL2724649 | 0.71 | ASPH (0.41) | ASPHGRIK1AKR1C3AKR1C2NOTUM | |
| Water SCHEMBL25435119 | 0.70 | ASPH (0.43) | ASPHAKR1C2NOTUMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |