Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461706 | 0.83 | CES2 (0.43) | ASPHAKR1C3AKR1C2TAS2R14KDM4E | |
| SCHEMBL8459788 | 0.77 | KDM4E (0.39) | ASPHAKR1C3AKR1C2KDM4EALDH1A1 | |
| SCHEMBL8460449 | 0.74 | CA1 (0.50) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL8459806 | 0.73 | ASPH (0.38) | ASPHAKR1C3AKR1C2TAS2R14NOTUM | |
| SCHEMBL14213196 | 0.73 | TPMT (0.46) | ASPHKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8463907 | 0.73 | TPMT (0.43) | AKR1C3AKR1C2NOTUMKDM4EALDH1A1 | |
| SCHEMBL8460193 | 0.73 | TTR (0.50) | AKR1C3AKR1C2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8462582 | 0.73 | TTR (0.50) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL8463842 | 0.73 | TPMT (0.52) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL8461644 | 0.72 | ASPH (0.40) | ASPHAKR1C3AKR1C2TAS2R14NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |