SCHEMBL8460307

SCHEMBL8460307

CCc1c(OC(N)=O)cccc1OC(=O)Nc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.52
FAAH O00519 3/20 0.48
HSP90AA1 P07900 1/20 0.48
GAA P10253 3/20 0.48
KMT2A Q03164 2/20 0.48
ATM Q13315 1/20 0.48
KDM4E B2RXH2 1/20 0.48
BLM P54132 1/20 0.48
NPSR1 Q6W5P4 1/20 0.46
ALDH1A1 P00352 3/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
MAPT P10636 1/20 0.42
SRD5A1 P18405 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8056391 0.86 RAB9A (0.52) RAB9AFAAHHSP90AA1GAAKMT2A
SCHEMBL29233095 0.86 RAB9A (0.55) RAB9AFAAHHSP90AA1GAAKMT2A
SCHEMBL29914183 0.86 RAB9A (0.55) RAB9AFAAHHSP90AA1GAAKMT2A
SCHEMBL2141997 0.85 GAA (0.58) RAB9AFAAHHSP90AA1GAAKMT2A
SCHEMBL25271584 0.79 RAB9A (0.60) RAB9AFAAHHSP90AA1GAAKMT2A
SCHEMBL8460308 0.77 RAB9A (0.56) RAB9AFAAHGAAKMT2AALDH1A1
SCHEMBL29914200 0.77 RAB9A (0.48) RAB9AFAAHHSP90AA1GAAKMT2A
SCHEMBL10708809 0.77 ATM (0.60) RAB9AFAAHGAAKMT2AATM
SCHEMBL30945831 0.76 MEN1 (0.41) KMT2ANPSR1ALDH1A1MAPT
SCHEMBL1840665 0.76 MEN1 (0.41) KMT2ANPSR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0748157-B1 METHOD FOR PRODUCING PESTICIDE COMPOSITION HOECHST SCHERING AGREVO GMBH (DE) 1999-10-20 EP claimed
US-5747417-A CARBAMOYLOXYPHENYL CARBAMATE HERBICIDE, OIL-IN-WATER EMULSION HOECHST SCHERING AGREVO GMBH (DE) 1998-05-05 US claimed
EP-0748157-A1 METHOD FOR PRODUCING PESTICIDE COMPOSITION Hoechst Schering AgrEvo GmbH (DE) 1996-12-18 EP claimed
WO-1996037101-A1 HERBICIDE FORMULATIONS AND METHODS FOR THEIR PREPARATION KEMIRA AGRO OY (FI) 1996-11-28 WO claimed
WO-1995023505-A1 METHOD FOR PRODUCING PESTICIDE COMPOSITION KEMIRA AGRO OY (FI) 1995-09-08 WO claimed
EP-0643555-A1 A METHOD OF PRODUCING HERBICIDAL GRANULAR PRODUCTS Hoechst Schering AgrEvo GmbH (DE) 1995-03-22 EP claimed
WO-1993005652-A1 A METHOD OF PRODUCING HERBICIDAL GRANULAR PRODUCTS KEMIRA AGRO OY (FI) 1993-04-01 WO claimed
US-20150144521-A1 STORAGE AIDS COMPRISING PLANT PROTECTANTS AND THEIR USE RKW SE (DE) 2015-05-28 US disclosed
WO-1996037101-A1 HERBICIDE FORMULATIONS AND METHODS FOR THEIR PREPARATION KEMIRA AGRO OY (FI) 1996-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150144521-A1 STORAGE AIDS COMPRISING PLANT PROTECTANTS AND THEIR USE ECPAS, BROX, TTPA RAB9A 2428/4885FAAH 1189/4885HSP90AA1 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.