Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CBS | P35520 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | RPA1 | P27694 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461900 | 0.86 | TSHR (0.46) | KMOTSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL28976679 | 0.70 | KMO (0.54) | KMO | |
| SCHEMBL30281285 | 0.70 | KMO (0.54) | KMO | |
| SCHEMBL23705007 | 0.68 | CA12 (0.42) | KMOTSHR | |
| SCHEMBL8036369 | 0.68 | MAOB (0.42) | TSHRSRD5A2 | |
| SCHEMBL8034546 | 0.68 | RXRA (0.36) | TSHRRXRA | |
| SCHEMBL3653503 | 0.68 | KMO (0.54) | KMO | |
| SCHEMBL25497742 | 0.67 | CCR2 (0.43) | KMOCCR2 | |
| SCHEMBL29877940 | 0.67 | CA12 (0.47) | KMOTSHR | |
| SCHEMBL23704956 | 0.67 | CA12 (0.41) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915831-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | Hoechst Schering AgrEvo S.A. (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003470-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | HOECHST SCHERING AGREVO S.A. (FR) | 1998-01-29 | — | — | WO | disclosed |