Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 6/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461563 | 0.89 | MAPT (0.35) | MAPTHSD17B10HTTGFERGPR55 | |
| SCHEMBL12981369 | 0.80 | ALDH1A1 (0.44) | HTTLMNACYP3A4MEN1KMT2A | |
| SCHEMBL2017897 | 0.78 | CES2 (0.42) | CA1CA2KMT2AALDH1A1HPGD | |
| SCHEMBL1965137 | 0.78 | TPMT (0.41) | CA1CA2CYP1A2CYP2D6SLC6A2 | |
| SCHEMBL2012718 | 0.78 | CES2 (0.42) | MAPTHTTCA1CA2LMNA | |
| SCHEMBL693987 | 0.77 | SMN1; SMN2 (0.50) | MAPTHSD17B10HTTLMNACYP3A4 | |
| SCHEMBL14530150 | 0.76 | TSHR (0.55) | HSD17B10CA12CA1CA2CA9 | |
| SCHEMBL19675411 | 0.76 | MEN1 (0.55) | MAPTHSD17B10HTTGFERCYP3A4 | |
| SCHEMBL28230027 | 0.75 | MAPT (0.52) | MAPTHSD17B10HTTGFERGPR55 | |
| SCHEMBL24905722 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114636-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2010-10-07 | — | — | WO | disclosed |
| US-7482112-B2 | Pattern forming method | FUJIFILM CORPORATION (JP) | 2009-01-27 | — | — | US | disclosed |
| US-20070172768-A1 | Pattern forming method | FUJIFILM CORPORATION (JP) | 2007-07-26 | — | — | US | disclosed |
| EP-0202458-B1 | CROSS-LINKED POLYALKENYL PHENOL BASED PHOTORESIST COMPOSITIONS | International Business Machines Corporation (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0202458-A2 | Cross-linked polyalkenyl phenol based photoresist compositions | International Business Machines Corporation (US) | 1986-11-26 | — | — | EP | disclosed |
| US-4221700-A | POLY(ALKYLATED ALKENYLPHENOL); POLYESTERS OF ALKYLTHIOALKANOIC ACIDS OR ORGANIC PHOSPHITE | MARUZEN OIL CO., LTD. (JP) | 1980-09-09 | — | — | US | disclosed |