Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609821 | 0.86 | FTO (0.54) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14690373 | 0.80 | ELANE (0.47) | KMT2ANPC1SMN1; SMN2ALDH1A1ELANE | |
| SCHEMBL373812 | 0.78 | THRB (0.43) | KMT2ANPC1RAB9AALDH1A1ELANE | |
| SCHEMBL13609830 | 0.77 | THRB (0.60) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4595840 | 0.77 | L3MBTL1 (0.48) | KMT2ASMN1; SMN2ALDH1A1ELANEMAPT | |
| SCHEMBL2589705 | 0.75 | KMT2A (0.37) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13609834 | 0.74 | THRB (0.45) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4884127 | 0.74 | TSHR (0.47) | KMT2ARAB9ASMN1; SMN2ALDH1A1ELANE | |
| SCHEMBL4752386 | 0.74 | ELANE (0.45) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30220166 | 0.74 | ELANE (0.45) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173826-B1 | HYDROGEL COMPOSITION AND HYDROGEL CONTACT LENSES MADE OF THE COMPOSITION | PEGAVISION CORP (TW) | 2019-02-13 | — | — | EP | disclosed |
| EP-3173826-A1 | HYDROGEL COMPOSITION AND HYDROGEL CONTACT LENSES MADE OF THE COMPOSITION | Pegavision Corporation (TW) | 2017-05-31 | — | — | EP | disclosed |
| EP-0674684-B1 | POLYMERISABLE YELLOW DYES AND THEIR USE IN OPHTHALMIC LENSES | ALCON LAB INC (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5662707-A | Polymerizable yellow dyes and their use in ophthalmic lenses | ALCON LABORATORIES, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5543504-A | REDUCE INTENSITY OF BLUE LIGHT | ALCON LABORATORIES, INC. (US) | 1996-08-06 | — | — | US | disclosed |
| US-5528322-A | AZO DYE GROUP-CONTAINING ACRYLATE AND METHACRYLATE MONOMERS | ALCON LABORATORIES, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5470932-A | Polymerizable yellow dyes and their use in opthalmic lenses | ALCON LABORATORIES, INC. (US) | 1995-11-28 | — | — | US | disclosed |
| EP-0674684-A1 | POLYMERISABLE YELLOW DYES AND THEIR USE IN OPHTHALMIC LENSES | ALCON LABORATORIES, INC. (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1995011279-A1 | POLYMERISABLE YELLOW DYES AND THEIR USE IN OPHTHALMIC LENSES | ALCON LABORATORIES, INC. (US) | 1995-04-27 | — | — | WO | disclosed |