SCHEMBL846331

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL846330	1.00	MAPK1 (0.59)	MAPK1KDM4EL3MBTL1ALDH1A1CA1
	SCHEMBL30372051	0.84	MAPK1 (0.61)	MAPK1KDM4EL3MBTL1ALDH1A1CA1
	SCHEMBL655582	0.84	MAPK1 (0.61)	MAPK1KDM4EL3MBTL1ALDH1A1CA1
	SCHEMBL9000473	0.83	MAPK1 (0.56)	MAPK1KDM4EL3MBTL1ALDH1A1CA1
	SCHEMBL7389658	0.83	KDM4E (0.57)	MAPK1KDM4EL3MBTL1ALDH1A1CA1
	SCHEMBL15894494	0.83	MAPK1 (0.56)	MAPK1KDM4EL3MBTL1ALDH1A1CA1
	SCHEMBL7389657	0.83	KDM4E (0.57)	MAPK1KDM4EL3MBTL1ALDH1A1CA1
	SCHEMBL31601570	0.83	MAPK1 (0.59)	MAPK1KDM4EL3MBTL1ALDH1A1CA1
	SCHEMBL846377	0.83	MAPK1 (0.59)	MAPK1KDM4EL3MBTL1ALDH1A1CA1
	SCHEMBL18940416	0.82	MAPK1 (0.54)	MAPK1KDM4EL3MBTL1ALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.