Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011812 | 0.71 | DAO (0.32) | DAO | |
| SCHEMBL1791619 | 0.71 | ALDH1A1 (0.38) | DAO | |
| SCHEMBL27459301 | 0.71 | DAO (0.32) | DAO | |
| Hydrochloric Acid SCHEMBL8535246 | 0.71 | — | — | |
| SCHEMBL1794431 | 0.70 | ALDH1A1 (0.37) | DAO | |
| SCHEMBL1924912 | 0.70 | DAO (0.31) | DAO | |
| SCHEMBL19323695 | 0.70 | MAPK14 (0.32) | DAO | |
| SCHEMBL2404545 | 0.68 | DAO (0.30) | DAO | |
| SCHEMBL2405178 | 0.68 | DAO (0.30) | DAO | |
| SCHEMBL14658384 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741145-B1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | claimed |
| EP-0741145-B1 | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | disclosed |
| CN-1043232-C | Catalyst composition and use of same for oligomerizing or polymerizing olefins | SHELL INT RESEARCH (NL) | 1999-05-05 | — | — | CN | disclosed |
| US-5756417-A | PHOSPHOLANE RING CONTAINING ORGANOMETALLIC POLYMERIZATION CATALYST TO CATALYZE OLEFINICALLY UNSATURATED HYDROCARBONS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0717754-B1 | CATALYST COMPOSITIONS | SHELL INT RESEARCH (NL) | 1997-12-03 | — | — | EP | disclosed |
| CN-1128539-A | Catalyst compositions | SHELL INT RESEARCH (NL) | 1996-08-07 | — | — | CN | disclosed |
| EP-0717754-A1 | CATALYST COMPOSITIONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-06-26 | — | — | EP | disclosed |
| EP-0638593-A1 | Catalyst compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-02-15 | — | — | EP | disclosed |
| WO-1995004087-A1 | CATALYST COMPOSITIONS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1995-02-09 | — | — | WO | disclosed |