SCHEMBL4479570

SCHEMBL4479570

CCB=[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.33
HTR6 P50406 1/20 0.33
SIGMAR1 Q99720 6/20 0.33
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31
HRH1 P35367 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL846366 0.78 RET (0.37) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL439955 0.77 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL2763485 0.76 SIGMAR1 (0.35) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL3380394 0.75 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL7643746 0.74 HTR2A (0.37) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL7621928 0.74 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
Hydrochloric Acid SCHEMBL7107235 0.74 SIGMAR1 (0.35) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL1921550 0.74 SIGMAR1 (0.35) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL6555624 0.73 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL7642384 0.73 RET (0.36) HTR2AHTR6SIGMAR1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0945471-B1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU KOSAN CO (JP) 2009-05-13 EP disclosed
US-6787499-B2 Catalyst for the production of α-olefin and α-olefin production method IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-09-07 US disclosed
US-20030134991-A1 Catalyst for the production of alpha-olefin and alpha-olefin production method thereof IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-07-17 US disclosed
US-6562918-B1 A catalyst for olefin polymerization, which is obtained by contacting (A) a compound of a transition metal of Groups 4 to 6 of the Periodic Table, (B) an organoaluminiumoxy compound, and optionally (C) a carrier with each other, and for which IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-05-13 US disclosed
US-6555633-B1 A alpha-olefin oligomerization catalyst obtained by contacting (a) a clay, clay mineral or ion-exchange layer compound with (b-1) a transition metal complex of group 4 to 6 of periodic table, and (a) is treated with organosilane compound IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-04-29 US disclosed
US-6395846-B1 COORDINATION CATALYST COMPRISING CLAY, ORGANOSILANE COMPOUND, WATER, AND TRANSITION METAL COMPLEX; QUALITY IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-05-28 US disclosed
US-6316557-B1 FOR PRODUCING HIGH QUALITY, STEREOSPECIFIC POLYOLEFINS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-11-13 US disclosed
EP-1085025-A1 CATALYST FOR OLEFIN POLYMERIZATION, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING OLEFIN POLYMER Idemitsu Petrochemical Co., Ltd. (JP) 2001-03-21 EP disclosed
EP-1066877-A1 CATALYSTS FOR $g(a)-OLEFIN PRODUCTION AND PROCESSES FOR PRODUCING $g(a)-OLEFIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-01-10 EP disclosed
EP-1026176-A1 CATALYST FOR OLEFIN POLYMER PRODUCTION, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING OLEFIN POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-08-09 EP disclosed
EP-0945471-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1999-09-29 EP disclosed