SCHEMBL8464235

SCHEMBL8464235

CCc1nn(C)c(S(=O)(=O)N(C(N)=O)c2nc(OC)cc(OC)n2)c1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 2/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL730603 0.79 ALDH1A1 (0.35) SMN1; SMN2CYP1A2KMT2ATSHR
SCHEMBL8465071 0.77 KMT2A (0.36) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C19
SCHEMBL5411955 0.74 GAA (0.50) SMN1; SMN2CYP1A2KMT2ATSHR
SCHEMBL3672158 0.73 KMT2A (0.38) SMN1; SMN2MEN1KMT2ATSHR
SCHEMBL1535828 0.72 KMT2A (0.45) SMN1; SMN2CYP1A2CYP3A4CYP2C19KMT2A
SCHEMBL6697530 0.69 MC4R (0.32)
SCHEMBL29220488 0.69 GAA (0.35)
SCHEMBL8380219 0.69 SMN1; SMN2 (0.34) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C19
SCHEMBL8175077 0.67 KMT2A (0.37) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C19
SCHEMBL8733579 0.66 SMN1; SMN2 (0.41) SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714602-B1 Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1999-05-12 EP claimed
EP-0708597-B1 HERBICIDAL COMPOSITIONS RHONE POULENC AGROCHIMIE (FR) 1998-09-16 EP claimed
US-5833733-A SOLID CORE, COATING; FUNGICIDE, HERBICIDE, NUTRIENTS; FOR RICE PADDYS NIHON BAYER AGROCHEM K.K. (JP) 1998-11-10 US disclosed