SCHEMBL6697530

SCHEMBL6697530

COc1cc(OC)nc(N(C(N)=O)S(=O)(=O)c2c(-c3nnn(C)n3)cnn2C)n1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MC4R P32245 4/20 0.32
MAPK8 P45983 1/20 0.30
MAPK10 P53779 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8465071 0.79 KMT2A (0.36)
SCHEMBL1535828 0.78 KMT2A (0.45)
SCHEMBL9216810 0.76 ACLY (0.32) MC4RMAPK8MAPK10
SCHEMBL27390244 0.76 TYK2 (0.33) MC4RMAPK8MAPK10
SCHEMBL3672158 0.74 KMT2A (0.38)
SCHEMBL9216825 0.74 GAA (0.35) MC4RMAPK8MAPK10
SCHEMBL28087093 0.71 GAA (0.43) MAPK8MAPK10
SCHEMBL730603 0.71 ALDH1A1 (0.35)
SCHEMBL27379393 0.70 FBP1 (0.37) MAPK8MAPK10
SCHEMBL9878291 0.70 GAA (0.44) MAPK8MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2836072-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT Dongbu Farm Hannong Co., Ltd. (KR) 2015-02-18 EP claimed
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2015-01-22 US claimed
WO-2013154396-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2013-10-17 WO claimed
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US claimed
EP-0708597-B1 HERBICIDAL COMPOSITIONS RHONE POULENC AGROCHIMIE (FR) 1998-09-16 EP claimed
US-10206399-B2 Herbicidal composition comprising uracil compound as active ingredient DONGBU FARM HANNONG CO., LTD. (KR) 2019-02-19 US disclosed
EP-2836072-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT Dongbu Farm Hannong Co., Ltd. (KR) 2015-02-18 EP disclosed
WO-2013154396-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2013-10-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT UNG, DDT, HDHD5 MC4R 4257/4885MAPK8 3832/4885MAPK10 4109/4885
US-20040171488-A1 N-aryl-uracils based Herbicides DDT, UNG, DDC MC4R 3906/4885MAPK8 4309/4885MAPK10 4637/4885
US-10206399-B2 Herbicidal composition comprising uracil compound as active ingredient UNG, DDT, HDHD5 MC4R 4257/4885MAPK8 3832/4885MAPK10 4109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.