SCHEMBL8464288

SCHEMBL8464288

CC(C)c1cccc(CCCc2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 1/20 0.48
CYSLTR1 Q9Y271 1/20 0.48
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
LMNA P02545 1/20 0.44
KCNH2 Q12809 2/20 0.44
CHRM2 P08172 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KIF11 P52732 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11167064 0.92 MAOA (0.50) CYSLTR2CYSLTR1RAB9AKCNH2SLC6A2
SCHEMBL29060315 0.86 CYSLTR2 (0.38) CYSLTR2CYSLTR1NPC1RAB9ASMN1; SMN2
SCHEMBL7029063 0.85 SLC6A2 (0.47) CYSLTR2CYSLTR1SLC6A2SLC6A4SLC6A3
SCHEMBL27535907 0.85 LPL (0.46) NPC1RAB9ASMN1; SMN2OPRM1DRD3
SCHEMBL20082361 0.83 KIF11 (0.50) DRD1KIF11HTR2A
SCHEMBL27657598 0.83 LPL (0.53) KCNH2OPRM1DRD3HTR2A
SCHEMBL18025549 0.83 CYP4F2 (0.46) CYSLTR2CYSLTR1NPC1RAB9ASMN1; SMN2
SCHEMBL5826355 0.82 RAB9A (0.57) NPC1RAB9ASMN1; SMN2LMNAMAOB
SCHEMBL2464423 0.81 LPL (0.54) KCNH2OPRM1DRD3HTR2A
Hydrochloric Acid SCHEMBL14157319 0.81 KIF11 (0.49) DRD1KIF11HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004435-A SEPARATION OF 2,6-DIETHYL ANILINE, METHYL SALICYLATE, DIPROPYLENE GLYCOL, 2-UNDECANONE, POLYETHYLENE GLYCOL, DIETHYLENE GLYCOL BUTYL ETHER, 2-PYRROLIDINONE, 3-NITROTOLUENE, ETHYL SALICYLATE AND TETRAMETHYSULFONE. BERG LLOYD (US) 1999-12-21 US disclosed