Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376299 | 0.85 | MEN1 (0.37) | MAPK1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27377442 | 0.79 | ALDH1A1 (0.51) | MAPK1ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL27531993 | 0.78 | KCNK3 (0.44) | MAPK1ALDH1A1NPC1RAB9AKCNK3 | |
| SCHEMBL27362439 | 0.77 | MTNR1A (0.37) | ALDH1A1SMN1; SMN2NPC1POLBLMNA | |
| SCHEMBL27383642 | 0.76 | CTSD (0.46) | MAPK1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27381448 | 0.75 | PPARA (0.43) | MAPTTSHR | |
| SCHEMBL27358392 | 0.74 | NAAA (0.57) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL8464421 | 0.72 | POLB (0.37) | MAPK1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8463044 | 0.71 | POLB (0.36) | MAPK1ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27377450 | 0.70 | CA9 (0.36) | MAPK1ALDH1A1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071540-C | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 2001-09-26 | — | — | CN | disclosed |
| CN-1140542-A | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1997-01-22 | — | — | CN | disclosed |