Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamide SCHEMBL8460578 | 0.94 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL8464926 | 0.82 | LMNA (0.47) | ALDH1A1HSD17B10CASP6LMNATDP1 | |
| SCHEMBL8463349 | 0.78 | GAA (0.40) | ALDH1A1HSD17B10CASP6CYP2C19LMNA | |
| SCHEMBL8464312 | 0.78 | CA12 (0.35) | ALDH1A1HSD17B10CYP2C9CYP2C19LMNA | |
| SCHEMBL8464561 | 0.77 | NT5E (0.48) | ALDH1A1HSD17B10CYP2C9CYP2C19LMNA | |
| SCHEMBL5409149 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL30084548 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL8462657 | 0.76 | HSD17B10 (0.59) | ALDH1A1HSD17B10LMNATSHRKDM4E | |
| Phosphoric Acid SCHEMBL8464326 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CASP6CYP2C9CYP2C19 | |
| SCHEMBL8464923 | 0.74 | PTPN1 (0.41) | ALDH1A1HSD17B10LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |