Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464469 | 0.82 | ALDH1A1 (0.41) | LMNAHPGDHSD17B10POLBTDP1 | |
| SCHEMBL8463349 | 0.80 | GAA (0.40) | LMNAHPGDHIF1AHSD17B10GAA | |
| SCHEMBL8460572 | 0.80 | ALDH1A1 (0.37) | HPGDGAAPOLBMCL1L3MBTL1 | |
| SCHEMBL8460490 | 0.80 | PARP1 (0.33) | LMNAHPGDHIF1AHSD17B10PKM | |
| SCHEMBL8464312 | 0.80 | CA12 (0.35) | LMNAHPGDHIF1AHSD17B10GAA | |
| SCHEMBL5664509 | 0.78 | LMNA (0.53) | LMNAHPGDHIF1AHSD17B10PTGS1 | |
| Sulfamide SCHEMBL8460578 | 0.77 | ALDH1A1 (0.46) | LMNAHPGDHIF1AHSD17B10GAA | |
| SCHEMBL8464923 | 0.76 | PTPN1 (0.41) | LMNAHPGDHSD17B10GAAMCL1 | |
| SCHEMBL8460910 | 0.76 | MEN1 (0.38) | HPGDHSD17B10MCL1L3MBTL1ALDH1A1 | |
| SCHEMBL8461162 | 0.76 | L3MBTL1 (0.42) | GAAL3MBTL1PKMMPLTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |