Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8367501 | 0.77 | ALOX5 (0.55) | PTPN1ALOX5MEN1MAPTKMT2A | |
| SCHEMBL8464926 | 0.76 | LMNA (0.47) | THRBLMNAL3MBTL1CA12CA2 | |
| SCHEMBL8463731 | 0.75 | MYC (0.41) | MAPTSMN1; SMN2LMNAL3MBTL1TSHR | |
| SCHEMBL4843096 | 0.75 | MAOB (0.48) | PTPN1HTR6ALOX5MEN1MAPT | |
| SCHEMBL4190433 | 0.75 | ACLY (0.50) | PTPN1ACLY | |
| SCHEMBL5973210 | 0.75 | IKBKB (0.51) | PTPN1HTR6MEN1MAPTKMT2A | |
| SCHEMBL8464469 | 0.74 | ALDH1A1 (0.41) | SMN1; SMN2LMNATSHRCA12CA2 | |
| SCHEMBL16583502 | 0.74 | SMN1; SMN2 (0.50) | PTPN1HTR6ALOX5MEN1MAPT | |
| SCHEMBL8462919 | 0.73 | PTPN1 (0.39) | PTPN1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8365978 | 0.73 | ALOX5 (0.55) | PTPN1HTR6ALOX5MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |