SCHEMBL8464646

SCHEMBL8464646

CCS(=O)(=O)Nc1cc(-n2c(=O)c(C)c(C(F)(F)F)n(C)c2=O)c(F)cc1C#N

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PGR P06401 7/20 0.38
BRD4 O60885 1/20 0.37
AR P10275 2/20 0.35
BCAT2 O15382 4/20 0.33
BCAT1 P54687 4/20 0.33
BRAF P15056 3/20 0.31
PSIP1 O75475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467306 0.90 BCAT2 (0.33) BCAT2BCAT1
SCHEMBL8853738 0.90 BCAT2 (0.33) PGRBRD4BCAT2BCAT1
SCHEMBL8467820 0.88 BCAT2 (0.31) BCAT2BCAT1
SCHEMBL7212890 0.82 PGR (0.39) PGRBRD4ARBCAT2BCAT1
SCHEMBL8319442 0.81 PGR (0.41) PGRBRD4ARBCAT2BCAT1
SCHEMBL7893225 0.80 BRD4 (0.30) BRD4
SCHEMBL7888852 0.77
SCHEMBL6308458 0.77 PGR (0.40) PGRBRD4AR
SCHEMBL8602347 0.77 BCAT2 (0.39) PGRBRD4ARBCAT2BCAT1
SCHEMBL7157679 0.77 PGR (0.39) PGRBRD4AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714602-B1 Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1999-05-12 EP disclosed
US-5641725-A Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US disclosed