SCHEMBL8467306

SCHEMBL8467306

Cc1c(C(F)(F)F)n(C)c(=O)n(-c2cc(NS(=O)(=O)C(F)(F)F)c(C#N)cc2F)c1=O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 6/20 0.33
BCAT1 P54687 6/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
KDM4E B2RXH2 1/20 0.30
PKM P14618 1/20 0.30
HTT P42858 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
TAS2R14 Q9NYV8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8853738 0.92 BCAT2 (0.33) BCAT2BCAT1
SCHEMBL8464646 0.90 PGR (0.38) BCAT2BCAT1
SCHEMBL8467820 0.89 BCAT2 (0.31) BCAT2BCAT1
SCHEMBL7893225 0.82 BRD4 (0.30)
SCHEMBL8853791 0.82 BCAT2 (0.35) BCAT2BCAT1CA1CA2
SCHEMBL7888852 0.79
SCHEMBL8323113 0.73 PGR (0.35) BCAT2BCAT1
SCHEMBL7671008 0.72 PGR (0.33) BCAT2BCAT1
SCHEMBL7212890 0.72 PGR (0.39) BCAT2BCAT1
SCHEMBL7627173 0.72 PGR (0.35) BCAT2BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714602-B1 Sulphonylaminophenyluracil herbicides for paddy field BAYER AGROCHEM KK (JP) 1999-05-12 EP disclosed
US-5641725-A Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1997-06-24 US disclosed
EP-0714602-A1 Sulphonylaminophenyluracil herbicides for paddy field NIHON BAYER AGROCHEM K.K. (JP) 1996-06-05 EP disclosed