SCHEMBL846495

SCHEMBL846495

c1c[nH]c(CNCCN(Cc2ncc[nH]2)Cc2ncc[nH]2)n1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 9/20 0.44
CXCR4 P61073 1/20 0.41
TERT O14746 1/20 0.41
ALOX15 P16050 1/20 0.41
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
LMNA P02545 1/20 0.39
GLA P06280 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
FPR2 P25090 1/20 0.38
KLK1 P06870 1/20 0.36
KLK5 Q9Y337 1/20 0.36
SLC40A1 Q9NP59 1/20 0.34
FDPS P14324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5355364 0.89 TAAR1 (0.39) TAAR1CXCR4TERTALOX15CYP2D6
SCHEMBL369710 0.83 TAAR1 (0.53) TAAR1TERTALOX15FPR2KLK1
SCHEMBL5355358 0.81 TAAR1 (0.52) TAAR1CXCR4TERTALOX15FPR2
SCHEMBL15948859 0.81 TAAR1 (0.52) TAAR1TERTALOX15CYP2D6TSHR
SCHEMBL2474802 0.79 TAAR1 (0.57) TAAR1TERTALOX15SMN1; SMN2FPR2
SCHEMBL370577 0.79 TAAR1 (0.53) TAAR1CXCR4TERTALOX15CYP2D6
SCHEMBL4775864 0.78 TERT (0.59) TAAR1TERTALOX15FPR2KLK1
SCHEMBL4985592 0.77 TAAR1 (0.47) TAAR1CXCR4TERTALOX15FPR2
SCHEMBL6225559 0.77 TAAR1 (0.47) TAAR1CXCR4TERTALOX15SMN1; SMN2
SCHEMBL1971764 0.77 TAAR1 (0.47) TAAR1CXCR4TERTALOX15FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2038356-B8 LIQUID HARDENING UNILEVER PLC (GB) 2011-06-22 EP claimed
EP-2038356-A1 LIQUID HARDENING Unilever PLC (GB) 2009-03-25 EP claimed
WO-2008003652-A1 LIQUID HARDENING UNILEVER PLC (GB) 2008-01-10 WO claimed
EP-1358309-A1 COMPOSITION AND METHOD FOR BLEACHIN G A SUBSTRATE UNILEVER PLC (GB) 2003-11-05 EP claimed
WO-2002077145-A1 COMPOSITION AND METHOD FOR BLEACHIN G A SUBSTRATE UNILEVER PLC (GB) 2002-10-03 WO claimed
EP-3906265-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA Inc. (US) 2021-11-10 EP disclosed
WO-2020142632-A1 RADICALLY POLYMERIZABLE COMPOSITIONS Polynt Composites USA, Inc. (US) 2020-07-09 WO disclosed
EP-2582744-A1 ACCELERATOR SOLUTION AND PROCESS FOR CURING CURABLE RESINS Akzo Nobel Chemicals International B.V. (NL) 2013-04-24 EP disclosed
EP-2521750-A1 CURING LIQUIDS OMG Additives Limited (GB) 2012-11-14 EP disclosed
WO-2011157673-A1 ACCELERATOR SOLUTION AND PROCESS FOR CURING CURABLE RESINS AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2011-12-22 WO disclosed
WO-2011083309-A1 CURING LIQUIDS UNILEVER PLC (GB) 2011-07-14 WO disclosed
EP-2038356-B8 LIQUID HARDENING UNILEVER PLC (GB) 2011-06-22 EP disclosed
WO-2010006861-A1 A PROCESS FOR TREATING STAINS ON FABRIC UNILEVER PLC (GB) 2010-01-21 WO disclosed
EP-2038356-A1 LIQUID HARDENING Unilever PLC (GB) 2009-03-25 EP disclosed
WO-2008003652-A1 LIQUID HARDENING UNILEVER PLC (GB) 2008-01-10 WO disclosed