Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465154 | 1.00 | KDM1A (0.50) | KDM1AMAOAMAOBMTNR1ASIGMAR1 | |
| SCHEMBL8465226 | 0.83 | ESR1 (0.41) | HTR2A | |
| SCHEMBL8465230 | 0.83 | ESR1 (0.41) | HTR2A | |
| SCHEMBL8465223 | 0.83 | ESR1 (0.41) | HTR2A | |
| SCHEMBL8348055 | 0.77 | ALOX5 (0.38) | — | |
| SCHEMBL8348060 | 0.77 | ALOX5 (0.38) | — | |
| SCHEMBL8348051 | 0.77 | ALOX5 (0.38) | — | |
| SCHEMBL7245074 | 0.76 | SIGMAR1 (0.50) | KDM1AMAOAMAOBMTNR1ASIGMAR1 | |
| SCHEMBL4132717 | 0.76 | MTNR1A (0.49) | MTNR1ASIGMAR1CYP19A1CYP11B1MTNR1B | |
| SCHEMBL30715531 | 0.76 | MTNR1A (0.49) | MTNR1ASIGMAR1CYP19A1CYP11B1MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998451-A | LIPOXYGENASE INHIBITORS | PFIZER INC (US) | 1999-12-07 | — | — | US | disclosed |
| US-5059609-A | Lipoxygenase inhibitors; leukotriene receptor blockers; psoriasis; antiulcer agents and myocardial infarctions | PFIZER INC. (US) | 1991-10-22 | — | — | US | disclosed |