Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625364 | 0.88 | LMNA (0.66) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL18147762 | 0.83 | MAPT (0.62) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL18147758 | 0.83 | MAPT (0.62) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL30725831 | 0.81 | HTT (0.60) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL8462703 | 0.81 | HTT (0.60) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL9836357 | 0.81 | MAPT (0.57) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL27470288 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL27137471 | 0.81 | KMT2A (0.69) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL25433021 | 0.79 | RORC (0.60) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL3004695 | 0.79 | HTT (0.69) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734363-B1 | FLUORINATION PROCESS | F2 CHEMICALS LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| US-5900502-A | Fluorination process | BNFL FLUOROCHEMICALS LIMITED (GB) | 1999-05-04 | — | — | US | disclosed |
| US-4766243-A | Electrophilic fluorination of aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |