SCHEMBL846752

SCHEMBL846752

COC1=C(C2=C(OC)C(=O)c3c(c(O)cc4c3C(=O)OC(C)C4)C2=O)C(=O)c2c(O)cc3c(c2C1=O)C(=O)OC(C)C3

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 1/20 0.53
KLK5 Q9Y337 1/20 0.53
MAOA P21397 5/20 0.48
MAOB P27338 2/20 0.48
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
OPRD1 P41143 1/20 0.46
KIT P10721 6/20 0.45
PDGFRA P16234 6/20 0.45
KDR P35968 6/20 0.45
FLT4 P35916 4/20 0.45
FLT3 P36888 4/20 0.45
PDGFRB P09619 2/20 0.42
MAP2K1 Q02750 2/20 0.42
ACVRL1 P37023 2/20 0.42
ALK Q9UM73 2/20 0.42
MAP2K2 P36507 1/20 0.42
FLT1 P17948 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL846317 0.85 KLK7 (0.73) KLK7KLK5MAOAMAOBKDM4E
SCHEMBL3366271 0.80 OPRD1 (0.62) KLK7KLK5MAOAMAOBKDM4E
SCHEMBL2314134 0.80 OPRD1 (0.62) KLK7KLK5MAOAMAOBKDM4E
SCHEMBL638027 0.76 MAOA (0.64) KLK7KLK5MAOAMAOBKDM4E
SCHEMBL13925624 0.75 KLK7 (0.67) KLK7KLK5MAOAMAOBKDM4E
SCHEMBL3366320 0.74 MEN1 (0.64) KLK7KLK5MAOAMAOBKDM4E
SCHEMBL13925623 0.72 ACHE (0.61) KLK7KLK5MAOAMAOBPOLB
SCHEMBL31371856 0.72 KLK7 (0.73) KLK7KLK5MAOAMAOBKDM4E
SCHEMBL29009458 0.72 KLK7 (0.73) KLK7KLK5MAOAMAOBKDM4E
SCHEMBL29885475 0.71 MAOA (0.57) KLK7KLK5MAOAMAOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026043908-A1 COMPOSITIONS AND METHODS TO IMPROVE SEQUESTRATION OF MYCOTOXINS AND THEIR USE IN DETOXIFICATION OF ANIMAL FEED AND ANIMAL PRODUCTION SYSTEMS ALLTECH, INC. (US) 2026-02-26 WO claimed
EP-3771487-A1 METHOD FOR THE SIMULTANEOUS DETERMINATION OF VARIOUS ANALYTES IN AN ENVIRONMENTAL SAMPLE AND / OR AN AGRICULTURAL RAW MATERIAL BASED ON CORE-SHELL MICROPARTICLES Bundesrepublik Deutschland, Vertreten durch den Bundesminister für Wirtschaft und Energie, dieser Vertreten durch den Präsidenten der (DE) 2021-02-03 EP claimed
EP-0448392-A2 Xanthomegnin, a known compound, is an antiparasitic agent MERCK & CO. INC. (US) 1991-09-25 EP claimed
US-5017603-A Xanthomegnin, a known compound, is an antiparasitic agent MERCK & CO., INC. (US) 1991-05-21 US claimed
JP-4217677-A None JP disclosed
JP-4217677-A None JP disclosed
EP-2841109-B1 PRODRUGS OF HYDROXYL-COMPRISING DRUGS ASCENDIS PHARMA AS (DK) 2026-04-15 EP disclosed
WO-2026043908-A1 COMPOSITIONS AND METHODS TO IMPROVE SEQUESTRATION OF MYCOTOXINS AND THEIR USE IN DETOXIFICATION OF ANIMAL FEED AND ANIMAL PRODUCTION SYSTEMS ALLTECH, INC. (US) 2026-02-26 WO disclosed
US-20250360073-A1 SOLUBILIZING PIGMENTS EXTRACTED FROM FUNGI FOR APPLICATIONS SUCH AS COSMETIC PRODUCTS ADLER JESSE (US) 2025-11-27 US disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
WO-2025059358-A1 FUNGAL STRAINS HAVING REDUCED OR ELIMINATED MYCOTOXIN, ETHANOL, AND/OR PIGMENT PRODUCTION CAPACITY THE FYNDER GROUP, INC. (US) 2025-03-20 WO disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
EP-0448392-A2 Xanthomegnin, a known compound, is an antiparasitic agent MERCK & CO. INC. (US) 1991-09-25 EP disclosed
US-5017603-A Xanthomegnin, a known compound, is an antiparasitic agent MERCK & CO., INC. (US) 1991-05-21 US disclosed
US-5017603-A Xanthomegnin, a known compound, is an antiparasitic agent MERCK & CO., INC. (US) 1991-05-21 US disclosed
US-5017603-A Xanthomegnin, a known compound, is an antiparasitic agent MERCK & CO., INC. (US) 1991-05-21 US disclosed
US-4963581-A PREVENTION OR TREATMENT OF BREAST CANCER; INHIBITOR OF AROMATASE, LOWERING ESTROGEN LEVEL TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-10-16 US disclosed
EP-0337413-A2 Naphthopyran derivatives and use thereof Takeda Chemical Industries, Ltd. (JP) 1989-10-18 EP disclosed
EP-0334421-A1 Antifungal fermentation product and derivatives and compositions thereof MERCK & CO. INC. (US) 1989-09-27 EP disclosed
US-4847284-A PYRROLIDINOL ANTIBIOTICS MERCK & CO., INC. (US) 1989-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 KLK7 2010/4885KLK5 2360/4885MAOA 164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.