Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 3/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260512 | 0.81 | CHRM1 (0.57) | TP53ERCC1ERCC4IDO1P2RX7 | |
| SCHEMBL29419329 | 0.81 | CHRM1 (0.57) | TP53ERCC1ERCC4IDO1P2RX7 | |
| Hydrochloric Acid SCHEMBL2532568 | 0.79 | CHRM1 (0.55) | TP53ERCC1ERCC4IDO1P2RX7 | |
| SCHEMBL28940593 | 0.79 | IDO1 (0.54) | TP53ERCC1ERCC4IDO1P2RX7 | |
| SCHEMBL1627494 | 0.78 | CTBP2 (0.59) | NR4A2SMN1; SMN2 | |
| SCHEMBL6299977 | 0.77 | GAA (0.48) | ERCC1ERCC4IDO1P2RX7GALR3 | |
| SCHEMBL30321024 | 0.77 | IDO1 (0.52) | TP53ERCC1ERCC4IDO1P2RX7 | |
| SCHEMBL657437 | 0.77 | IDO1 (0.52) | TP53ERCC1ERCC4IDO1P2RX7 | |
| SCHEMBL20595771 | 0.76 | IDO1 (0.49) | TP53ERCC1ERCC4IDO1P2RX7 | |
| SCHEMBL7617723 | 0.76 | AKR1B1 (0.39) | TDP1L3MBTL1CYP3A4MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765351-B1 | AMIDATION OF ESTER FUNCTIONALIZED HYDROCARBON POLYMERS | EXXON CHEMICAL PATENTS INC (US) | 1999-01-13 | — | — | EP | disclosed |
| US-5627259-A | REACTION OF OLEFIN POLYMERS WITH CARBON MONOXIDE AND ALCOHOL THEN REACTION OF ESTER WITH POLYAMINE COMPOUND RELEASING ALCOHOL COMPOUND | EXXON CHEMICAL PATENTS INC. (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0765351-A1 | AMIDATION OF ESTER FUNCTIONALIZED HYDROCARBON POLYMERS | EXXON CHEMICAL PATENTS INC. (US) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995035330-A1 | AMIDATION OF ESTER FUNCTIONALIZED HYDROCARBON POLYMERS | EXXON CHEMICAL PATENTS INC. (US) | 1995-12-28 | — | — | WO | disclosed |