Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | ERCC1 | P07992 | 4/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30321024 | 1.00 | IDO1 (0.52) | IDO1ERCC1ERCC4CYP1A2CYP3A4 | |
| SCHEMBL260323 | 0.86 | L3MBTL1 (0.55) | IDO1ERCC1ERCC4P2RX7TDP1 | |
| SCHEMBL29718886 | 0.86 | L3MBTL1 (0.55) | IDO1ERCC1ERCC4P2RX7TDP1 | |
| SCHEMBL28940593 | 0.85 | IDO1 (0.54) | IDO1ERCC1ERCC4CYP1A2CYP3A4 | |
| SCHEMBL29419329 | 0.83 | CHRM1 (0.57) | IDO1ERCC1ERCC4CYP1A2CYP3A4 | |
| SCHEMBL260512 | 0.83 | CHRM1 (0.57) | IDO1ERCC1ERCC4CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL2532568 | 0.82 | CHRM1 (0.55) | IDO1ERCC1ERCC4CYP2C9P2RX7 | |
| SCHEMBL20796876 | 0.82 | GALR3 (0.55) | IDO1ERCC1ERCC4CYP1A2CYP3A4 | |
| SCHEMBL29712851 | 0.82 | IDO1 (0.50) | IDO1ERCC1ERCC4CYP1A2CYP3A4 | |
| SCHEMBL4686080 | 0.82 | IDO1 (0.50) | IDO1ERCC1ERCC4CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369587-A | A kind of production technology of high-purity high-yield Envidor | 新沂市永诚化工有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-109053410-A | It is a kind of synthesize 1- hydroxy-cyclohexyl formic acid new process and application | 兰博尔开封科技有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-108863774-A | A kind of 2,4 dichloro benzene chloroacetic chloride synthetic method | 石家庄市绿丰化工有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108658913-A | A kind of method of synthetic pesticide Envidor key intermediate | 石家庄市绿丰化工有限公司 | 2018-10-16 | — | — | CN | claimed |
| US-20240417379-A1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO., LTD (JP) | 2024-12-19 | — | — | US | disclosed |
| US-12116351-B2 | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO., LTD (JP) | 2024-10-15 | — | — | US | disclosed |
| CN-113880764-B | Sinomenine derivative and preparation method and application thereof | 北京师范大学 | 2023-04-18 | — | — | CN | disclosed |
| US-11584744-B2 | Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them | UNIVERSITY OF WASHINGTON (US) | 2023-02-21 | — | — | US | disclosed |
| US-11584744-B2 | Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them | UNIVERSITY OF WASHINGTON (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220380322-A1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO., LTD (JP) | 2022-12-01 | — | — | US | disclosed |
| US-11434207-B2 | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO., LTD (JP) | 2022-09-06 | — | — | US | disclosed |
| CN-113880764-A | Sinomenine derivative and preparation method and application thereof | 北京师范大学 | 2022-01-04 | — | — | CN | disclosed |
| US-4262072-A | ABRASION RESISTANT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4258189-A | ANTHRAPYRIDINE MODIFIED ADDITION POLYMERS | DYNAPOL (US) | 1981-03-24 | — | — | US | disclosed |
| US-4249011-A | CURING AGENTS FOR ADDITION PHOTOPOLYMERIZATION | MINNESOTA MINING AND MANUFACTURING COMPANY | 1981-02-03 | — | — | US | disclosed |
| WO-1981000011-A1 | POLY(ETHYLENICALLY UNSATURATED ALKOXY)HETEROCYCLIC COMPOUNDS AND CROSSLINKED POLYMERIC COATINGS | MINNESOTA MINING & MFG (US) | 1981-01-08 | — | — | WO | disclosed |
| EP-0006254-A1 | Benzoin oxime derivatives, process for their preparation, compositions containing such derivatives and method for their use as fungicides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-01-09 | — | — | EP | disclosed |
| US-4073936-A | Hypolipidemic allene carboxylic esters | SANDOZ, INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4011339-A | ANTIINFLAMMATORY AGENTS | SANDOZ, INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-3992396-A | TRANQUILIZERS, HYPNOTICS | SANDOZ, INC. (US) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380322-A1 | P2X4 RECEPTOR ANTAGONIST | P2RX7, P2RX1, P2RX2 | IDO1 1912/4885ERCC1 4026/4885ERCC4 4269/4885 |
| US-20240417379-A1 | P2X4 RECEPTOR ANTAGONIST | P2RX7, P2RX1, P2RX2 | IDO1 1876/4885ERCC1 3024/4885ERCC4 3623/4885 |
| US-12116351-B2 | P2X4 receptor antagonist | P2RX7, P2RX1, P2RX2 | IDO1 1912/4885ERCC1 4026/4885ERCC4 4269/4885 |
| US-11434207-B2 | P2X4 receptor antagonist | P2RX7, P2RX1, P2RX2 | IDO1 1912/4885ERCC1 4026/4885ERCC4 4269/4885 |
| US-11584744-B2 | Inhibitors of type 1 methionyl-tRNA synthetase and methods of using them | AARS1, EMG1, GARS1 | IDO1 1989/4885ERCC1 3093/4885ERCC4 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.