Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354188 | 0.93 | TSHR (0.33) | TSHRFAAH | |
| SCHEMBL12045927 | 0.88 | ACHE (0.30) | — | |
| SCHEMBL9987743 | 0.88 | ACHE (0.32) | TSHR | |
| SCHEMBL15691409 | 0.88 | ACHE (0.32) | TSHR | |
| SCHEMBL9988049 | 0.84 | MAPT (0.32) | — | |
| SCHEMBL13784564 | 0.84 | FAAH (0.30) | FAAH | |
| SCHEMBL9988867 | 0.83 | — | — | |
| SCHEMBL9987712 | 0.82 | KDM4E (0.35) | FAAH | |
| SCHEMBL14269209 | 0.82 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL2367797 | 0.81 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883152-A | HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER | NIPPON OIL AND FATS CO., LTD. (JP) | 1999-03-16 | — | — | US | claimed |
| US-5883152-A | HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER | NIPPON OIL AND FATS CO., LTD. (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0425831-B1 | Contact lens | NIPPON OILS & FATS CO LTD (JP) | 1995-05-03 | — | — | EP | disclosed |