SCHEMBL2367797

SCHEMBL2367797

C=C(CC(=O)O)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9354188 0.88 TSHR (0.33) TSHR
SCHEMBL12045927 0.83 ACHE (0.30)
SCHEMBL15691409 0.83 ACHE (0.32) TSHR
SCHEMBL9987743 0.83 ACHE (0.32) TSHR
SCHEMBL12045933 0.82
SCHEMBL8467787 0.81 MGAM (0.34) TSHR
SCHEMBL35807 0.81 TSHR (0.51) TSHR
Methacrylic Acid SCHEMBL29583152 0.80 TSHR (0.47) TSHR
Methacrylic Acid SCHEMBL15856026 0.80 TSHR (0.47) TSHR
SCHEMBL333002 0.80 TSHR (0.50) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 US disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 EP disclosed